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蛋白質(zhì)相關(guān)工具

1 pI計(jì)算:https://www.protpi.ch/Calculator/ProteinTool

2 膜蛋白二級(jí)結(jié)構(gòu)預(yù)測(cè),可判斷跨膜區(qū) https://harrier.nagahama-i-bio.ac.jp/sosui/

  Classification and Secondary Structure Prediction of Membrane Proteins(pdf)

MemBrain: Transmembrane protein structure prediction http://www.csbio.sjtu.edu.cn/bioinf/MemBrain/

  上海交通大學(xué)模式識(shí)別與生物信息學(xué)研究組沈紅斌教授生物信息學(xué)在線平臺(tái)

4 STRING 蛋白互作 https://cn.string-db.org

UniProt :https://www.uniprot.org。Uniprot是 Universal Protein 的英文縮寫,是信息最豐富、資源最廣的蛋白質(zhì)數(shù)據(jù)庫。它由整合Swiss-Prot、 TrEMBL 和 PIR-PSD 三大數(shù)據(jù)庫的數(shù)據(jù)而成。他的數(shù)據(jù)主要來自于基因組測(cè)序項(xiàng)目完成后,后續(xù)獲得的蛋白質(zhì)序列。

Cell-PLoc 2.0 www.csbio.sjtu.edu.cn/bioinf/Cell-PLoc-2/

Cell-PLoc 2.0: A package of web-servers for predicting subcellular localization of proteins in different organisms

NP文章詳細(xì)解釋如何操作

7 Pumba-Human https://pumba.dcsr.unil.ch/

The PUMBA database is a resource of reference 1D-SDS-PAGE migration patterns for proteins from human and other organisms. Its purpose is to validate or troubleshoot western blot experiments, but also to provide information about proteoforms.

Mylonas R, Potts A, Waridel P, Barblan J, Conde Rubio MDC, Widmann C, Quadroni M. A Database of Accurate Electrophoretic Migration Patterns for Human Proteins. J Mol Biol. 2023 Feb 28;435(4):167933. doi: 10.1016/j.jmb.2022.167933. Epub 2022 Dec 26. PMID: 36581244.